HISTOPATHOLOGICAL EVALUATION OF PARANASAL SINUS OPACITIES ON TEMPORAL BONE TOMOGRAPHY IN PATIENTS WITH CHRONIC OTITIS MEDIA
1Kızıltepe Devlet Hastanesi, KBB, Mardin, Turkey2Yıldırım Beyazıd Üniversitesi Tıp Fakültesi, KBB, Ankara, Turkey Objective: This study is designed to analyse asymptomatic sinus opacities histopathologically in comparison to chronic rhinosinusitis(CRS).
Material and Method: This is a prospective study conducted in the Department of Otolaryngology between December2008- November 2009. From 20 patients who have asymptomatic paranasal sinus opacities on temporal computed tomography (CT), who were selected during their preoperative evaluation out of 147 chronic otitis media (COM) patients, maxillary sinus biopsies were taken intraoperatively from asymptomatic paranasal sinus opacities after timpanoplasty/ timpanomastoidectomy. Control grup consisted of biopsies of 8 patients who have functional endoscopic sinus surgery (FESS) for CRS. Histopathologic analysis and comparison were made statistically between two grups.
Results: Lenfoid follicule formation, congestion and pathological grade were found to be different between the groups (p=0,017, p=0,011, p=0,013).Epithelial integrity (p=0.072), goblet cell hyperplasia(GCH) (p=0.238), squamous metaplasia (p=0.320), thickness of basement membrane (BM) (p=0.11), submucosal gland hyperplasia(SMGH) (p=0.089), eosinophils (p= 0.328), neutrophils (p=0.381), lymphocytes (p=0.438), plasma cells (p=1.00), macrophages (p=0.55), calcification (p=0.063), lymphatic dilatation (p= 1.00), subepithelial edema (p= 0.285), polipoid degeneraion (p=1.00) were statistically similar in both groups. Similarly, the calcification detected by pathology and CT were not significantly correlated (κ=0.379 ve p=0.075).
Conclusion: Asymptomatic incidental paranasal sinus opacities seen on temporal CT in patients of chronic otitis media are similiar to CRS histopathologically.
Keywords : Chronic otitis media(COM),temporal bone tomography, paranasal sinüs,histopathological examination