EVALUATION OF INFLAMMATION PARAMETERS IN COMPLETE BLOOD COUNT IN PATIENTS DIAGNOSED WITH VESTIBULAR MIGRAINE

Methods: 30 patients diagnosed with vestibular migraine and 40 healthy individuals were included. The medical records of patients who were evaluated in the otorhinolaryngology-vertigo clinic during a vertigo attack and consulted to the neurology clinic, and were diagnosed with vestibular migraine were evaluated. Routine complete blood count results were used to calculate the neutrophil-, platelet-, eosinophil- and basophil-lymphocyte ratios, lymphocyte-monocyte ratio and mean platelet volume. The vestibular migraine and the control groups were compared statistically in terms of neutrophil-, platelet-, eosinophil-, basophil-lymphocyte ratios, lymphocyte-monocyte ratio and mean platelet volume.

Results: The mean platelet volume was significantly higher in the vestibular migraine group than the control group (p < 0.05). Platelet, neutrophil, lymphocyte, eosinophil and monocyte counts and neutrophil-/eosinophil-lymphocyte ratios and lymphocyte-monocyte ratio did not differ significantly (p> 0.05) between the groups. The basophil count was significantly higher in the vestibular migraine group (p < 0.05). The platelet-lymphocyte ratio was significantly lower (p < 0.05), the basophil-lymphocyte ratio was significantly higher in the vestibular migraine group (p < 0.05).

Conclusions: Mean platelet volume, basophil-lymphocyte ratio, and basophil count were significantly higher, and platelet-lymphocyte ratio was significantly lower in the vestibular migraine group. Our results showed that systemic inflammation may contribute to the pathogenesis of vestibular migraine. Keywords : Vestibular Migraine, Inflammation, Complete Blood Count Cell Ratios, Mean Platelet Volume, Basophil Lymphocyte Ratio, Basophil