BONE and SOFT TISSUE TUMORS OF THE HEAD and NECK CAUSING DIFFICUILTY IN DIFFERENTIAL DIAGNOSIS: EVALUATION OF 190 CASES WITH LITERATURE
1Bezmialem Vakıf Üniversitesi Tıp Fakültesi, Tıbbi Patoloji Anabilim Dalı, İstanbul, Türkiye2Bezmialem Vakıf Üniversitesi Tıp Fakültesi, Kulak Burun Boğaz Anabilim Dalı, İstanbul, Türkiye Introduction: Primary bone and soft tissue tumors of head and neck region are very rare. Only 5-15% of all sarcomas seen in adulthood are located in the head and neck region. The rates of bone and soft tissue tumors are 20% and 80%, respectively. The aim of this retrospective study is to evaluate the demographic features and diagnostic distributions of bone and soft tissue tumors located in the head and neck region in comparison with the literature.
Material-Method: All cases diagnosed with head and neck mesenchymal tumors at the pathology department of the medical faculty hospital since 2015 were retrospectively reviewed from the hospital's information system. They were classified according to the demographic characteristics, localization and diagnosis, compared with the literature.
Results: Mean age for all cases was 40.8, age range was 2-85. While the mean age of soft tissue cases was 42.2(2-85), it was 34.4(8-70) for bone tumors. 56%(n: 107) of all cases were male, 44%(n: 83) of them were female. Considering the specific localizations in the head and neck region, 28%(n: 53) of 190 cases were in the neck region with the highest rate. 81%(n: 154) of them were soft tissue-derived, 19%(n: 36) were bone-derived. 93%(n: 144) of soft tissue tumors were benign, 7%(n: 10) of them were malignant. 88%(n: 32) of bone tumors were benign, 6%(n: 2) of them were malignant, and 6%(n: 2) of them were Langerhans cell histiocytosis included in hematopoietic neoplasms of the bone.
Conclusion: When the complex structure of the head and neck region and the varying histological features of bone and soft tissue tumors come together, difficulties in diagnosis and clinical management are inevitable. In our study, we tried to reflect the demographic and diagnostic distribution of head and neck mesenchymal tumors in comparison with the literature. As a result, it was observed that the data obtained were mostly compatible with the literature.
Keywords : Head and neck, bone and soft tissue neoplasms, diagnostic distribution