EFFECT OF SEPTOPLASTY ON THE MEAN PLATELET VOLUME AND INFLAMMATION MARKERS
1Selçuk Üniversitesi Tıp Fakültesi KBB Anabilim Dalı, KBB, Konya, Turkey2Yıldırım Beyazıt Üniversitesi Tıp Fakültesi KBB Anabilim Dalı, KBB, Ankara, Turkey
3Kaçkar Devlet Hastanesi , KBB, Rize, Turkey Objective: Nasal septal deviation is an obstructive pathology and can be related to inflammation. This study aimed to investigate the relationship between nasal septum deviation leading to obvious nasal obstruction and certain variables including mean platelet volume (MPV), platelet distribution width (PDW), neutrophil/lymphocyte ratio (NLR), and platelet/lymphocyte ratio (PLR). The study will also examine the effect of this operation on this relationship.
Materials and Methods: This is a prospective study. The study sample included 29 patient group participants that had septoplasty indications, and 31 control group participants that were healthy volunteers. Control and patient groups were compared with regard to MPV, PDW, NLR, PLR, platelet count and white blood cell (WBC) counts. The significance level was accepted as 0.05 in the relevant statistical analyses.
Findings: The preoperative MPV and PDW levels were found to be higher in the patient group than the control group. The difference between them was statistically significant (p < 0.05). In the patient group, the researchers observed a decrease of 0.72 units in the MPV value and 0.91 units in the PDW value, and an increase of 6.72 units in the platelet count at the end of the month following the operation compared with the relevant values in the preoperative period (p < 0.05).
Result: The MPV and PDW values were high in the patients with nasal septum deviation requiring surgery. Moreover, these high MPV and PDW values were found to normalize after the operation.
Keywords : Inflammation, mean platelet volume, nasal airway obstruction, nasal surgical procedures, platelet activation