KBB-Forum 2005 , Cilt 4, Sayı 3

EFFECT OF FLUTICASONE PROPIONATE NASAL DROPS ON INTRAOCULAR PRESSURE

Dr. Didem SERİN1, Dr. Serap KÖYBAŞI2, Dr. Gürsoy ALAGÖZ1, Dr. Fahrettin YILMAZ2, Dr. Şahap KÜKNER2
1İzzet Baysal Tıp Fakültesi, GÖZ AD, Bolu, Türkiye
2İzzet Baysal Tıp Fakültesi, KBB AD, Bolu, Türkiye
Purpose: We aimed to investigate the effect of fluticasone propionate nasal drops on intraocular pressure.

Method: Ninety eight eyes of 49 adult patients who were prescribed fluticasone nasal drops for nasal poliposis or allergic rhinitis and did not have any systemic or ocular risk factors that may affect intraocular pressure were included in the study. Intraocular pressure levels of all patients were measured before the treatment. Intraocular pressure measurements were repeated after an average treatment period of 9,53 ± 2,13 weeks. Pretreatment and posttreatment intraocular pressure values were compared statistically.

Results: There was no statistically significant difference between pretreatment and posttreatment intraocular pressure levels (p=0.516 and p=0.940 for the right and left eyes, respectively).

Conclusion: Our study demonstrates that treatment with fluticasone propionate nasal drops does not cause a significant change in the intraocular pressure. However, larger groups of patients are required for further evaluation of the risk for increasing intraocular pressure. Keywords : Fluticasone propionate, nasal drops, intraocular pressure