KBB-Forum 2019 , Cilt 18, Sayı 2

THE SIGNIFICANCE OF SYSTEMIC INFLAMMATORY MARKERS IN THE DIFFERENTIAL DIAGNOSIS OF BENIGN AND MALIGN MASSES IN PATIENTS WITH PAROTID GLAND TUMORS

Dr. Nur YÜCEL EKİCİ1, Dr. Gökhan KURAN1
1Adana City Training and Research Hospital, Department of Otorhinolaryngology, Adana, Türkiye Objective: In this study, we aimed to evaluate the importance of neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and systemic inflammation index (SII) in the differential diagnosis of benign and malign masses in patients with parotid gland tumors.

Methods: Medical records of 134 patients, operated for parotid gland mass in our clinic between January 2017 and December 2018 examined retrospectively. Patients were evaluated for age, sex, pre-operative complete blood count, post-operative histopathological diagnosis and presence of chronic disease. Patients were separated into 2 groups according to their post-operative histopathological diagnosis as benign tumors (group 1) and malignant tumors (group 2).

Results: There was no statistically significant difference between the groups in terms of age and sex (p>0.05). Mean NLR and PLR were significantly higher in group 2 than with group 1 (p= 0.041 and p= 0.027; respectively). Although SII was higher in group 2, no statistically significant difference was found between the groups (p= 0.128).

Conclusion: The NLR and PLR may be used to differential diagnosis of benign and malign masses in patients with parotid gland tumors. These parameters are inexpensive and easy to use. But further studies are needed in this issue with a larger patient group. Keywords : Parotid tumors, parotidectomy, neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, systemic inflammation index