KBB-Forum 2013 , Cilt 12, Sayı 4

PRIMARY KAPOSI SARCOMA OF THE PAROTID GLAND IN A HUMAN IMMUNODEFICIENCY VIRUS (HIV) - NEGATIVE PATIENT

Utku AYDİL, MD1; Nalan AKYÜREK, MD2; Hassan LATİFİ, MD1; Ayşe HELVACI, MD2; Yusuf KIZIL, MD1
1Gazi Üniversitesi Tıp Fakültesi, KBB Hastalıkları AD, Ankara, Türkiye
2Gazi Üniversitesi Tıp Fakültesi , Patoloji AD, Ankara, Türkiye
Kaposi Sarcoma (KS) is almost always a malignancy of immunocompromised patients who are mostly Human Immunodeficiency Virus (HIV) - positive and occurrence in an immunocompetent patient is extremely rare. A 54-year-old female patient admitted with a neck mass, and the mass slowly enlarged despite antibiotic treatment during three months follow-up period. Fine needle aspiration biopsy (FNAB) was not diagnostic. A core biopsy was done and Human Herpes Virus (HHV) -8 positive KS was diagnosed. HIV serology, magnetic resonance imaging (MRI) and positron emission tomography/computed tomography (PET/CT) was obtained. The patient was HIV negative. MRI revealed that the mass was located within the parotid tail. In PET/CT, a submandibular lymph node with low pathological activity was also detected. Excision of the parotid tail and a selective neck dissection (levels I-III) was performed. Final pathological examination revealed HHV-8 positive KS. Since surgical margins were negative, no adjuvant therapy was administered. Although quite rare, primary KS can develop within parotid gland in HIV negative individuals. Surgical resection of the lesion with clear margins is mainstay of the treatment. Keywords : Kaposi Sarcoma, Parotid Gland, HIV, HHV-8, surgery